MicroSensors and MicroActuators Georgia Tech MEMS group
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Development of 3-D Micro-Electrode Arrays (MEAs) for neuronal culturing, stimulation and recording Swaminathan Rajaraman, Maxine McClain, James D. Ross, Mark G. Allen The congruence of MEMS and biology is a natural thing as the size of cells and cellular networks matches very well with microfabricated structures. The goal of this project is the development of 3-D microelectrode arrays with coupled fluidic functionalities. We have demonstrated 2 different technologies: laser micromachining and metal transfer micromolding to fabricate 3-D MEAs. Further we have shown 2-D and 3-D neuronal culture growth, survival (for several days in-vitro) and tissue slice electrophysiological recordings (in acute in-vitro studies). Sponsors: NIH Other Projects: Exploring applications of 3-D MEA à
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